Topics

    BACKGROUND AND ORIGIN OF PSC – Chaired by: J. Wilson

  1. Origin, characteristics and function of hepatic stellate cells. H. Tsukamoto, M. Pinzani
  2. Similarities and differences between hepatic and pancreatic stellate cells. M. Pinzani, C. Kordes, H. Tsukamoto, M. Apte
  3. Characteristics of pancreatic stellate cells. How do PSCs differ to fibroblasts and myofibroblasts? M. Bachem
  4. Stellate cell system: The role of stellate cells in different organs and systems: M. Pinzani, H. Tsukamoto, C. Kordes, J. Oh, C. Logston
  5. Bone marrow derived PSC in experimental acute and chronic pancreatitis. R. Jaster, A. Masamune,
  6. Does EMT contribute to the population of PSC? M. Erkan, J. Kleeff
  7. ISOLATION AND CULTIVATION OF PSC – Chaired by: T. Gress

  8. Density gradient centrifugation to isolate the fat storing phenotype from normal pancreas. M. Apte
  9. Outgrowth method to isolate activated PSC from fibrotic pancreas and desmoplastic cancer tissue. H. Habisch, M. Bachem.
  10. Characteristics, similarities and differences in gene-expression and secretions between PSC isolated from tumor stroma, chronic pancreatitis and normal pancreas. M. Buchholz, M. Erkan, M. Bachem, H. Habisch, R. Jaster, T. Gress
  11. Differences in PSC isolation, cell biology and characteristics between mouse, rat, human. P. Phillips, A. Masamune
  12. Purity and contaminants of PSC isolated by different methods. M. Erkan, H. Friess
  13. ACTIVATION AND SIGNALING PATHWAYS OF PSC Chaired by: M. Bachem

  14. Markers of quiescent PSC, markers of activated PSC. C. Kordes, A. Masamune, M Apte
  15. Changes in PSC gene expression after activation on plastic in comparison to inactive PSC. M. Pinzani, P. Phillips
  16. Inactivation of PSC. J. Oh, P. Phillips
  17. Conservation of the quiescent fat storing phenotype of stellate cells in culture. J. Oh
  18. Role of immortalized PSC in cell biology of pancreas. R. Hwang, C. Logsdon, R. Jaster, M. Buchholz
  19. Intracellular signalling pathways of PSC. R. Jaster, M. Buchholz
  20. ROLE OF PSC IN PANCREATIC DISEASES Chaired by: M. Apte

  21. Role of PSC in fibrogenesis and fibrolysis. M. Apte, M. Bachem, A. Masamune
  22. Role of PSC in pancreatic fibrosis due to pancreatitis
    1. Alcoholic pancreatitis G. Klöppel
    2. Autoimmune pancreatitis B. Sipos, S. Detlefsen
  23. Role of PSC in tumor progression and resistance to therapy. R. Hwang, C. Logsdon, A. Masamune, P. Phillips
  24. Activation of the PSC around early metaplastic/dysplastic lesions in human and mouse pancreas. I. Esposito, B. Sipos, C. Michalski, C. Reiser-Erkan, M.Erkan
  25. Angiogenesis – anti-angiogenesis. A. Masamune, M. Apte, R. Hwang, C. Logsdon, M. Erkan
  26. Plasticity of stellate cells – Stellate cells as progenitor cells. C. Kordes, H. Tsukamoto, M. Pinzani, R. Jaster

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